근심과 신피질 측두엽간질의 뇌파, 신경영상검사 및 수술예후 비교
Comparison of Electroencephalography, Neuroimaging Studies and Surgical Outcome between Mesial and Neocortical Temporal Lobe Epilepsies
김광수, Andrew J Cole,
소속 상세정보
김광수 ( Kim Kwang-Soo )
고신대학교 의과대학 신경과학교실
( Andrew J Cole )
Massachusetts General Hospital, MGH Epilepsy Service
KMID : 0877220010050020151
Abstract
Purpose: To compare the diagnostic value of electroencephalography (EEG), MRI and PET studies and surgical outcome in patients with medically refractory temporal lobe epilepsy due to hippocampal sclerosis (HS) versus temporal lobe lesions (TLL).
Methods: Records of 122 consecutive patients who underwent surgery for epilepsy from January 1993 to April 2000 were retrieved from the MGH Epilepsy Surgery Database. Fifty eight patients with temporal lobe epilepsy due to pathologically proven HS or TLL were identified and presurgical interictal and ictal EEG, MRI, and 2-[(18)F]fluoro-2-deoxy-D-glucose (FDG)-PET data and surgical outcome were reviewed. Patients with dual or normal pathology were excluded. Pathologically proven HS was present in 32 patients, and 26 patients has temporal lobe lesions (cortical dysplasia in 6 patients, vascular malformation in 6, gliomas in 5, DNET in 4, heterotopia in 1, other pathologies in 4). Comparisons of the diagnostic value of EEG, MRI and FDG-PET studies were performed in 43 patients who were seizure-free after epilepsy surgery. Among 43 patients, HS was in 24 patients and TLL in 19.
Results: The occurrence of abnormal interictal and ictal EEG, MRI and FDG-PET findings in the side of operation was not significantly different between patients with HS and with TLL respectively. There was no significant difference in at least one year follow-up surgical outcome between the two groups.
Conclusions: Diagnostic value of presurgical interictal and ictal EEG, MRI and FDG-PET findings, and surgical outcome were not different in patients with mesial versus neocortical temporal lobe epilepsies.
키워드
측두엽간질; 뇌파; 신경영상; 수술예후
Temporal lobe epilepsy; Electroencephalography (EEG); Neuroimaging; Surgical outcome
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