간질 환자의 삶의 질에 대한 평가 : QOLIE(Quality of Life in Epilepsy)-89를 이용한 연구
The Evaluation of the Quality of Life in Epileptic Patients : The Study of QOLIE(Quality of Life in Epilepsy)-89
김준태, 신대수, 김종기, 황인용, 최성민, 김병채, 김명규, 조기현,
소속 상세정보
김준태 ( Kim Joon-Tae )
전남대학교 의과대학 신경과학교실
신대수 ( Shin Dae-Su )
전남대학교 의과대학 신경과학교실
김종기 ( Kim Jong-Ki )
전남대학교 의과대학 신경과학교실
황인용 ( Hwang In-Yong )
전남대학교 의과대학 신경과학교실
최성민 ( Choi Seong-Min )
전남대학교 의과대학 신경과학교실
김병채 ( Kim Byeong-Chae )
전남대학교 의과대학 신경과학교실
김명규 ( Kim Myeong-Kyu )
전남대학교 의과대학 신경과학교실
조기현 ( Cho Ki-Hyun )
전남대학교 의과대학 신경과학교실
KMID : 0877220010050020177
Abstract
Purpose: Patients with epilepsy experience the impairment of Quality of life (QOL). The objective of this study was to investigate the ’Quality of Life’ in epileptic patients and the influences of clinical factors upon QOL in epileptic patients.
Methods: Total 138 epileptic patients (male : 77, female : 61) were recruited for the study. The Quality of Life in Epilepsy (QOLIE)-89 was applied to evaluate QOL in epileptic patients. We gathered data about clinical variables (seizure type, frequency, duration of disease, number of antiepileptic drug, and depression) and socio-demographic variables (age, sex, marriage, employment, and education), and compared each variables in use of QOLIE-89 score.
Results: Depression influenced negatively the most of all subscales (16 of 20 subscales) and overall score (p<0.01), and was the most significant inverse predictor of QOL in patients with epilepsy. Patients who were seizure-free in the past year reported better QOL than those with seizure-doing (p<0.05). Patients with polypharmacy showed lower scores at overall QOL, health discouragement, language, and overall score than those with monopharmacy (p<0.05). Male showed lower score than female at the scale of sexual relation (p<0.05), but higher scores at scales of health perception, overall health, and physical health (p<0.05). Highly-educated group (> or =16 year) had higher score at overall score and emotional well-being (p<0.05). However, age, marital state, employment, seizure type, and duration of disease did not affect QOL significantly.
Conclusions: Sex, education, number of AEDs, depression, and seizure free state were major socio-clinical factors affecting QOL in patients with epilepsy. It is suggested that physician should recognize these factors and manage appropriately for improving the QOL.
키워드
Epilepsy; Quality of life; QOLIE-89; Depression; Seizure free state
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