청각 전구증상을 보인 복합부분발작 환자 : 뇌파와 뇌자기공명영상 소견에 대한 연관성
Auditory Auras in Complex Partial Epilepsy : Correlation of EEG and MRI Findings
양광익, 박선아, 김규식, 박형국, 허경, 박수철, 이병인,
소속 상세정보
양광익 ( Yang Kwang-Ik )
순천향대학교 의과대학 신경과학교실
박선아 ( Park Sun-Ah )
연세대학교 의과대학 신경과학교실
김규식 ( Kim Gyu-Sik )
연세대학교 의과대학 신경과학교실
박형국 ( Park Hyung-Kook )
순천향대학교 의과대학 신경과학교실
허경 ( Heo Kyoung )
연세대학교 의과대학 신경과학교실
박수철 ( Park Soo-Chul )
연세대학교 의과대학 신경과학교실
이병인 ( Lee Byung-In )
연세대학교 의과대학 신경과학교실
KMID : 0877220020060010007
Abstract
Background: Auditory auras are rare but may have localizing value in patients presenting with epilepsy. We conducted the study to correlate the clinical characteristics, EEG and MRI findings in patients with auditory auras.
Methods: We identified 44 epileptic patients (23 male, 21 female) with auditory auras from Yonsei epilepsy registry between 1989 and 2000. All had routine EEG and MRI. These patients were subjected for the classification of lobar epilepsies based on the clinical-EEG-MRI correlations, which aimed at demonstrating 1) the association of auditory auras with temporal lobe epilepsy and 2) the localizing value of auditory auras to the neocortical temporal lobe epilepsy.
Results: Auditory auras were elementary in twenty-three, complex in eighteen, and both in three. Twenty patients described auditory aura only, and 24 patients described other associated auras including cephalic sensation, emotional, experiential, autonomic, epigastric, visual, vestibular, and somatosensory phenomena. The classification based on the Clinic-EEG-MRI correlations revealed that 33 of 44 patients (75%) were classified as temporal lobe epilepsy, however, it did not suggest any strong correlations with neocortical temporal lobe epilepsy.
Conclusion: Auditory aura was strongly related with the temporal lobe epilepsy but it did not provide any further localizing value of seizure origin in patients with TLE.
키워드
간질; 측두엽; 청각 전구증상
c-Fos protein; Medial vestibular nucleus
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