발작과 의식저하를 동반한 급성 Methyl Bromide 중독 2예
Two Cases of Methyl Bromide Intoxication with Seizures and Altered Mental State
조광덕, 임수빈, 이순금, 최성훈, 김태훈, 한군희, 송경일,
소속 상세정보
조광덕 ( Jo Kwang-Deog )
울산대학교 의과대학 강릉아산병원 신경과학교실
임수빈 ( Yim Soo-Bin )
울산대학교 의과대학 강릉아산병원 신경과학교실
이순금 ( Lee Soon-Keum )
울산대학교 의과대학 강릉아산병원 신경과학교실
최성훈 ( Chio Seong-Hoon )
울산대학교 의과대학 서울아산병원 가정의학교실
김태훈 ( Kim Tae-Hoon )
울산대학교 의과대학 서울아산병원 가정의학교실
한군희 ( Han Koon-Hee )
울산대학교 의과대학 강릉아산병원 내과학교실
송경일 ( Song Kyung-Il )
울산대학교 의과대학 강릉아산병원 내과학교실
KMID : 0877220030070020125
Abstract
Methyl bromide is presently used as a fumigant for insects in soil, grains or fruit in storage or transport. It is a neurotoxic agent and has been responsible a number of deaths or acute poisonings among occupationally exposed persons. We report 2 patients, who had worked fumigation warehouse, presented with seizures and altered mental state. The serum concentrations of bromide were elevated 32.9 and 42.5 mg/l, respectively. Brain MRI showed bilateral symmetric high signal intensities in the splenium of corpus callosum, the globus pallidus, the quadrigeminal plate, the periaqueductal gray matter, the red nucleus, the substantia nigra, the medial lemniscus, the pontine tegmentum, the dentate nucleus, and the medulla. There was no brain lesion in the other patient. Appropriate and supervised handling of the chemical and regular education to workers are important to avoid the risk of methyl bromide poisoning.
키워드
Methyl bromide;Neurotoxicity;Seizure
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