소아의 비전형적 롤란도 간질에서 정량적 뇌파분석
Quantitative EEG Analysis in Atypical Rolandic Epilepsies of Childhood
오지영, 이향운, 조현지, 최경규, 박기덕, 김정연,
소속 상세정보
오지영 ( Oh Jee-Young )
이화여자대학교 의과대학 신경과학교실
이향운 ( Lee Hyang-Woon )
이화여자대학교 의과대학 신경과학교실
조현지 ( Cho Hyun-Ji )
이화여자대학교 의과대학 신경과학교실
최경규 ( Choi Kyoung-Gyu )
이화여자대학교 의과대학 신경과학교실
박기덕 ( Park Kee-Duk )
이화여자대학교 의과대학 신경과학교실
김정연 ( Kim Jeong-Yeon )
인제대학교 의과대학 상계백병원 신경과학교실
KMID : 0877220050090010053
Abstract
Purpose: Benign childhood epilepsy with centrotemporal spikes (BCECT) or benign rolandic epilepsy (BRE) is not always benign in clinical or neuroimaging features. Recent studies have reported atypical forms of rolandic epilepsy with abnormal neurologic and/or neuroimaging findings, sometimes, also with poor seizure control. We investigated whether there are any differences in linear and nonlinear EEG analysis in typical and atypical rolandic epilepsies of childhood.
Methods: Ten patients with typical BRE group and seven patients with atypical BRE group were included in this study. We selected artifact-free 10-second epochs from 19 electrodes of 10-20 international EEG system from each patient. The power spectrum was calculated in delta, theta, alpha, beta, and gamma frequency ranges. The fractal dimension was analyzed as a nonlinear EEG analysis. We analyzed both EEGs with interictal spikes and without focal slowing or epileptiform activities.
Results: The spectral EEG analysis showed a significant increase of absolute and relative power of delta with decrease of alpha bands in atypical BRE group compared to typical group. There was no statistical difference in fractal dimension between the two groups.
Conclusion: Atypical BRE group showed enhanced delta and decreased alpha power, suggesting a cortical dysfunction in this group with poor clinical outcome.
키워드
Benign childhood epilepsy with centrotemporal spikes (BCECT) ; Benign rolandic epilepsy (BRE)
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