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³²¿øÁö¿ª °í¿¬·É Àα¸¿¡¼­ ´ç´¢º´ÀÇ À¯º´·ü Prevalence of diabetes mellitus in the elderly of Namwon county, South Korea

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Abstract

¸ñÀû : ´ç´¢º´ÀÇ À¯º´·üÀº Áö¿ªÀû, ÀÎÁ¾ÀûÀÎ Â÷À̸¦ º¸À̸ç, Çѱ¹¿¡¼­ ´ç´¢º´ÀÇ À¯º´·üÀº ÇöÀúÇÑ Áõ°¡¸¦ º¸ÀÌ°í ÀÖÀ¸³ª, Áö¿ª»çȸ Àα¸¸¦ ´ë»óÀ¸·Î °æ±¸´çºÎÇϰ˻縦 ÀÌ¿ëÇÑ ¿ªÇÐÁ¶»ç´Â Àû´Ù. ÀÌ¿¡ ÀúÀÚ µîÀº Àü¶óºÏµµ ³²¿ø½Ã Áö¿ª ÁֹεéÀ» ´ë»óÀ¸·Î ¼¼°èº¸°Ç±â±¸
(WHO)
Áø´Ü±âÁØ°ú ¹Ì±¹´ç´¢º´ÇÐȸ (ADA) Áø´Ü±âÁØ¿¡ ÀÇÇÏ¿© ´ç´¢º´ÀÇ À¯º´·üÀ» »êÃâÇÏ°í °ü·ÃµÈ ÀÎÀÚ¸¦ ºÐ¼®ÇÏ¿´À¸¸ç, Çѱ¹Àο¡¼­ WHO ¹× ADA Áø´Ü±âÁØÀ» Àû¿ëÇÔ¿¡ µû¶ó ³ªÅ¸³ª´Â Ư¼ºÀ» ºñ±³ ºÐ¼®ÇÏ¿´´Ù.
¹æ¹ý : 1999³â 3¿ù 22ÀϺÎÅÍ 1999³â 7¿ù 14ÀϱîÁö Àü¶óºÏµµ ³²¿ø½Ã Áö¿ª¿¡¼­ ¹«ÀÛÀ§·Î 3°³ ¸é°ú 2°³ µ¿À» ¼±Á¤ÇÏ¿© ÀÌ°÷¿¡ °ÅÁÖÇÏ´Â 40¼¼ ÀÌ»óÀÇ ¼ºÀÎ 1445¸íÀ» ´ë»óÀ¸·Î ÇÏ¿´´Ù. WHO Áø´Ü±âÁØ°ú ADA Áø´Ü±âÁØÀ» ÀÌ¿ëÇÏ¿© DM ¹× IGT, IFGÀÇ À¯º´·üÀ» »êÃâÇÏ¿´°í,
´ë»óÀÚµéÀÇ ¿¬°ü ÀÎÀÚ¸¦ ºÐ¼®ÇÏ¿´´Ù.
°á°ú : ³²¿ø Áö¿ª¿¡¼­ÀÇ 40¼¼ ÀÌ»ó ¼ºÀÎ 665¸í¿¡¼­ 1999³â ´ëÇѹα¹ Ãß°èÀα¸·Î ¿¬·ÉÀ» º¸Á¤ÇÑ À¯º´·üÀº, WHO Áø´Ü±âÁØÀ¸·Î DM, IGT´Â °¢°¢ 13.7%, 13.8%, ADA¿¡¼­ Á¦¾ÈÇÑ Áø´Ü±âÁØÀ» Àû¿ëÇϸé DM, IGT, IFG´Â °¢°¢ 15.8%, 12.8%, 5.7%¿´°í, ÀÌ¹Ì Áø´ÜµÈ ´ç´¢º´
ȯÀÚ´Â
5.8%¿´´Ù. µÎ Áø´Ü±âÁØ¿¡ µû¶ó ºÐ·ùµÈ ´ë»óÀÚ¸¦ ºñ±³ÇÏ¿´À» ¶§ IFG±ºÀ» Á¦¿ÜÇÑ µÎ Áø´Ü±âÁØÀÇ ÀÏÄ¡µµ´Â 0.94·Î ¸Å¿ì ³ôÀº ¾ç»óÀ» ³ªÅ¸³»¾ú´Ù (p<0.001). °æ±¸´çºÎÇÏ°Ë»ç 2½Ã°£ÈÄ Ç÷´ç 200 mg/dL (11.1 mmol/L)¿¡ ÇØ´çÇÏ´Â °øº¹Ç÷´ç ±âÁØÄ¡´Â ROC ºÐ¼®À» ÅëÇØ 114.5
mg/dL
(6.4 mmol/L)·Î ÃßÁ¤µÇ¾ú´Ù. ADA Áø´Ü±âÁØ¿¡ µû¸¥ ´ç´¢º´ ¹× ³»´ç´ÉÀå¾ÖÀÇ À¯º´·üÀº ¿¬·É Áõ°¡¿¡ µû¶ó Áõ°¡ÇÏ¿´´Ù (p<0.05). üÁú·®Áö¼ö´Â Àüü ´ë»óÀÚ¿¡¼­ Æò±Õ 23.8 3.4, NGT±º¿¡¼­ 23.75 3.46, DM±º¿¡¼­ 23.67 3.16À̾úÀ¸¸ç, üÁú·®Áö¼öÀÇ Áõ°¡¿¡ µû¸¥ DM, IGT,
IFGÀÇ
À¯ÀÇÇÑ À¯º´·üÀÇ Â÷ÀÌ´Â °üÂûÇÒ ¼ö ¾ø¾ú´Ù. Ç㸮-¾ûµ¢ÀÌ µÑ·¹ºñÀÇ Áõ°¡¿¡ µû¶ó DMÀÇ À¯º´·üÀº À¯ÀÇÇÑ Áõ°¡¸¦ º¸¿´´Ù (p<0.05). Ç÷¾Ð ¹× Áß¼ºÁö¹æÀÇ Áõ°¡¿¡ µû¶ó DMÀÇ À¯º´·üÀº À¯ÀÇÇÑ Áõ°¡¸¦ º¸¿´°í, ÀÌ»óÁöÁúÇ÷ÁõÀÌ ÀÖ´Â °æ¿ì DM À¯º´·üÀÇ ºñ±³À§Çèµµ´Â À¯ÀÇÇÏ°Ô
³ô¾Ò´Ù
(Odds ratio 2.29, 95% CI: 1.16-3.49).
°á·Ð : 40¼¼ ÀÌ»óÀÇ Àα¸¿¡¼­ Çѱ¹ÀÇ ´ç´¢º´ÀÇ À¯º´·üÀº ¼­±¸¿Í ºñ½ÁÇÑ ¼öÁØÀ̸ç 7, 80³â´ë¿¡ ºñÇØ ÇöÀúÇÑ Áõ°¡¸¦ º¸¿´´Ù. ¶ÇÇÑ Çѱ¹ÀÇ Á¤»óÀÎ, ´ç´¢º´ ¹× ³»´ç´ÉÀå¾Ö ȯÀÚµéÀÇ ºñ¸¸µµ´Â ¼­±¸¿¡ ºñÇØ ³ôÁö ¾Ê¾ÒÀ¸¸ç, ´ç´¢º´ÀÇ À¯º´¿¡ ¹ÌÄ¡´Â ¿µÇâµµ ÀÛ¾ÒÀ¸³ª,
¼öÀûÀÎ
Á¦ÇÑÁ¡ÀÌ ÀÖ¾î Çѱ¹ÀÇ ´ç´¢º´ À§ÇèÀÎÀÚ¿¡ ´ëÇÑ Áö¿ªÀû, ÀÎÁ¾Àû Ư¼ºÀ» ¿¬±¸Çϱâ À§ÇÑ ´ë±Ô¸ðÀÇ ÀϹÝÀα¸¸¦ ´ë»óÀ¸·Î ÇÑ ¿ªÇÐÁ¶»ç°¡ ÇÊ¿äÇÒ °ÍÀ¸·Î »ç·áµÈ´Ù. WHO¿Í ADA¿¡¼­ Á¦½ÃÇÑ Áø´Ü ±âÁØÀÇ °øº¹ Ç÷´ç Àå¾Ö¸¦ Á¦¿ÜÇÑ ÀÏÄ¡µµ ³ô¾ÒÀ¸¸ç, °øº¹ Ç÷´çÀÌ Áø´Ü ±âÁØÀ¸·Î
Áß¿äÇϳª, Çѱ¹ ÀϹÝ
Àα¸ÀÇ ´ç´¢º´ Áø´Ü¿¡¼­´Â ½ÄÈÄ 2½Ã°£ Ç÷´çÀÇ Á߿伺µµ °£°úÇÒ ¼ö´Â ¾øÀ» °ÍÀ¸·Î »ç·áµÈ´Ù.

Background : Significant ethnic and geographic differences exist in the prevalence of diabetes mellitus, which has increased dramatically in South Korea. But a few population-based studies were performed in South Korea. The purpose of this study
was to
determine the prevalence of diabetes mellitus, impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) by the World Health Organization (WHO) and the American Diabetic Association (ADA) diagnostic categories, and to investigate their
associated risk factors.
Methods : Between march 22, 1999 and July 14, 1999, a random sampling of 1445 residents over 40 year of age in five villages in the Namwon county of South Korea was carried out. Among these subjects, 665 (46.0%) participants completed 75 g OGTT.
WHO and
ADA diagnostic criteria were used for the diagnosis of diabetes mellitus, IGT and IFG. Detailed questionnaire were performed and anthropometric data were collected.
Results : After age-adjustment for population projection for Korea (1999), the prevalence of diabetes and IGT were 13.7% and 13.8% with WHO criteria, while the prevalence of diabetes, IGT and IFG were 15.8%, 12.8% and 5.7% with ADA criteria. The
age-adjusted prevalence of previously diagnosed diabetes was 5.8%. The level of agreement between WHO and ADA diagnostic criteria except IFG was high (¥ê=0.94; p<0.001). The ROC curve analysis determined FSG of 114.5 mg/dL (6.4 mmol/L) to yield
optimal
sensitivity and specificity corresponding to a PP2SG 200 mg/dL (11.1 mmol/L). The prevalence of diabetes and IGT with ADA diagnostic criteria rose with increasing age (p<0.05). The difference in the prevalence of diabetes, IGT and IFG by BMI was
not
significant. The prevalence of diabetes rose with increase in the waist-hip ratio. The prevalence of diabetes was increased in subjects with dyslipidemia

Å°¿öµå

Diabetes Mellitus; Experimental; Prevalence;

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KoreaMed
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