말단비대증 환자에서 임상 호전을 보인 1예
Acromegaly improved with sandostatin LAR treatment
이영주, 조현철, 하승형, 장지원, 김종화, 황흥곤,
소속 상세정보
이영주 ( Lee Young-Joo )
부천세종병원 내과학교실
조현철 ( Jo Hyun-Chul )
부천세종병원 내과학교실
하승형 ( Ha Seung-Hyung )
부천세종병원 내과학교실
장지원 ( Jang Ji-Won )
부천세종병원 내과학교실
김종화 ( Kim Jong-Hwa )
부천세종병원 내과학교실
황흥곤 ( Hwang Heung-Kon )
부천세종병원 내과학교실
KMID : 0882420070730060643
Abstract
중증도의 확장성심근증을 동반한 말단비대증 환자에 서 Sandostatin LAR 치료 이후에 좌심실기능의 호전과 뇌하수체 종양의 크기의 감소를 관찰할 수 있었던 환자 1예를 경험하였기에 보고하는 바이다.
Cardiovascular disease is the most frequent cause of death in patients with acromegaly. Recently, long-term treatment with a somatostatin analogue (Sandostatin LAR) has been shown to be effective in controlling growth hormone (GH) and insulin like growth factor-1 (IGF-1) hypersecretion in most patients with acromegaly. Along with the effectiveness in the hormone profile, Sandostatin LAR has been reported to be effective for tumor mass shrinkage and clinical symptom improvement. We have encountered a female acromeglic patient with severe dilated cardiomyopathy and the patient was treated with Sandostatin LAR After treatment for 12 months, as seen by follow up echocardiography, the overall cardiac function was significantly improved. We report the case with a review of the literature
키워드
확장성심근증;말단비대증
Acromegaly;Dilated cardiomyopathy
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