복막투석 환자에서 발생한 후천성 천공성 피부병의 성공적 치료 1예
Successful Treatment of Acquired Perforating Dermatosis in a Peritoneal Dialysis Patient Using Oral Isotretinoin
김희서, 이상희, 이미지, 주민숙, 이동영, 문경협, 김범,
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김희서 ( Kim Hui-Seo )
Gwangmyeong Sungae Hospital Department of Internal Medicine
이상희 ( Lee Sang-Hee )
Veterans Health Service Medical Center Department of Internal Medicine
이미지 ( Lee Mi-Ji )
Veterans Healthcare System Medical Center Department of Pathology
주민숙 ( Jue Mihn-Sook )
Veterans Health Service Medical Center Department of Dermatology
이동영 ( Lee Dong-Young )
Veterans Health Service Medical Center Department of Internal Medicine
문경협 ( Moon Kyoung-Hyub )
Veterans Health Service Medical Center Department of Internal Medicine
김범 ( Kim Beom )
Veterans Health Service Medical Center Department of Internal Medicine
Abstract
Acquired perforating dermatosis (APD) triggers severe itching, and is observed most often in patients with diabetes mellitus (DM) and chronic kidney disease (CKD). Various treatments, such as topical steroids, topical and oral retinoids, allopurinol, and ultraviolet B (UVB) phototherapy, have been used. However, as the precise etiology is unknown, there are a lack of well-established treatment guidelines. We report a peritoneal dialysis patient with a diagnosis of APD who was resistant to topical steroids, phototherapy, allopurinol, and topical retinoids. Severe pruritus persisted, which compromised his ability to lead a normal life. As a final treatment option, we used oral isotretinoin and the patient experienced a dramatic improvement.
키워드
Chronic kidney disease peritoneal dialysis; Isotretinoin; Pruritus
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