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Allergen-Specific Immunotherapy Against Allergic Respiratory Diseases
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°¼ºÀ± ( Kang Sung-Yoon )
Gachon University College of Medicine Gil Medical Center Department of Internal Medicine
¾ç¹Î¼® ( Yang Min-Suk )
SMG-SNU Boramae Medical Center Department of Internal Medicine
ÀÌ»ó¹Î ( Lee Sang-Min )
Gachon University College of Medicine Gil Medical Center Department of Internal Medicine
ÀÌ»óÇ¥ ( Lee Sang-Pyo )
Gachon University College of Medicine Gil Medical Center Department of Internal Medicine
Abstract
Allergen-specific immunotherapy (AIT) can alter the natural course of an allergic disease. It is widely held that the efficacy of a given therapeutic modality should be proven by well-designed double-blind placebo-controlled randomized clinical trials and meta-analyses. In this article, the therapeutic efficacy of AIT for allergic respiratory diseases, such as allergic rhinitis and asthma, is reviewed. In addition, potential clinical and experimental predictors of the treatment response are reviewed for AITs requiring long-term treatment, and for some allergic rhinitis and asthma patients who show no response to AIT.
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Rhinitis, allergic; Asthma; Immunotherapy; Immunologic desensitization; Immunologic hyposensitization
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