진행성 전립선암의 치료: 국내 전립선암 전문가로 구성된 Prostate Cancer Summit (PCAS) 2016을 통한 전립선암 치료 지침의 확인
Management of Patients With Advanced Prostate Cancer: Establishment of Treatment Guidelines Through Prostate Cancer Summit (PCAS) 2016 Composed of Korean Prostate Cancer Experts
장춘태, 김형준, 김명기, 박성우, 박승철, 박재영, 이동현, 이승환, 전황균, 정재훈, 정현, 조문기, 홍성후, 곽철, 이지열, 권동득, 김청수, 전성수,
소속 상세정보
장춘태 ( Jang Chun-Tae )
Sungkyunkwan University School of Medicine Samsung Medical Center Department of Urology
김형준 ( Kim Hyung-Joon )
Konyang University College of Medicine Department of Urology
김명기 ( Kim Myung-Ki )
Chonbuk National University Medical School Department of Urology
박성우 ( Park Sung-Woo )
Pusan National University Yangsan Hospital Department of Urology
박승철 ( Park Seung-Chol )
Wonkwang University Hospital Department of Urology
박재영 ( Park Jae-Young )
Korea University College of Medicine Department of Urology
이동현 ( Lee Dong-Hyeon )
Ewha Womans University School of Medicine Department of Urology
이승환 ( Lee Seung-Hwan )
Yonsei University College of Medicine Department of Urology
전황균 ( Jeon Hwang-Gyun )
Sungkyunkwan University School of Medicine Samsung Medical Center Department of Urology
정재훈 ( Chung Jae-Hoon )
Sungkyunkwan University School of Medicine Samsung Medical Center Department of Urology
정현 ( Jeong Hyeon )
Seoul National University College of Medicine SMG-SNU Boramae Medical Center Department of Urology
조문기 ( Jo Moon-Ki )
Korea Cancer Center Hospital Department of Urology
홍성후 ( Hong Sung-Hoo )
Catholic University College of Medicine Department of Urology
곽철 ( Kwak Cheol )
Seoul National University College of Medicine Seoul National University Hospital Department of Urology
이지열 ( Lee Ji-Youl )
Catholic University College of Medicine Department of Urology
권동득 ( Kwon Dong-Deuk )
Chonnam National University Medical School Department of Urology
김청수 ( Kim Choung-Soo )
University of Ulsan College of Medicine Asan Medical Center Department of Urology
전성수 ( Jeon Seong-Soo )
Sungkyunkwan University School of Medicine Samsung Medical Center Department of Urology
Abstract
Purpose: The Advanced Prostate Cancer Consensus Conference (APCCC) 2015 was based on topics with controversy in the field of advanced prostate cancer. To understand the Korean urologists perspective regarding the issues, we have conducted a questionnaire named Prostate Cancer Summit (PCAS) 2016, with 9 important subtopics.
Materials and Methods: Total 9 subtopics have been decided and questions were developed regarding each subtopic. The questions were based on that of APCCC 2015 and translated into Korean for better understanding. Total 51 panelists have voted online on 85 different questions.
Results: The survey concluded that testosterone should be measured as a diagnostic criterion for castration resistance prostate cancer (CRPC) and that consensus was reached on issues such as the use of androgen receptor pathway inhibitors in the treatment of predocetaxel and postdocetaxel in CRPC patients. In addition, 76% of the participants agreed that imaging tests were needed before new treatment in CRPC patients, and a majority of participants agreed that periodic imaging tests are necessary regardless of symptoms during treatment for CRPC. However, some issues, such as the use of prostate-specific antigen-based triggers for remediation in CRPC patients, the endocrine manipulation in nonmetastatic CRPC patients, and the onset of treatment in asymptomatic metastatic CRPC patients, were not agreed.
Conclusions: The results from PCAS 2016 has addressed some of the issues with controversy. Although the voting results are subjective, it will help guide treatment decisions in topics with less evidence.
키워드
Advenced prostate cancer; CRPC; PCAS2016; APCCC2015
원문 및 링크아웃 정보
등재저널 정보