Gorham-Stout Disease of the Cranial Bone Causing Recurrent Cerebrospinal Fluid Rhinorrhea and Bacterial Meningitis
김진아, 손효신, 윤성준, 권형민,
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김진아 ( Kim Jin-Ah )
Seoul National University College of Medicine SMG-SNU Boramae Medical Center Department of Neurology
손효신 ( Son Hyo-Shin )
Seoul National University College of Medicine SMG-SNU Boramae Medical Center Department of Neurology
윤성준 ( Yoon Sung-Joon )
Seoul National University College of Medicine SMG-SNU Boramae Medical Center Department of Neurology
권형민 ( Kwon Hyung-Min )
Seoul National University College of Medicine SMG-SNU Boramae Medical Center Department of Neurology
Abstract
Gorham-Stout disease (GSD) is a rare disorder characterized by the proliferation of vascular tissue in the bones and the progressive destruction of bones. We report the case of a 25-year-old man with GSD involving the cranial bone, who presented with recurrent cerebrospinal fluid (CSF) rhinorrhea and bacterial meningitis. Because of the rarity of this disease, arriving at the diagnosis of GSD was challenging. After excluding other etiologies, the clinical and radiological findings helped us to make a diagnosis of GSD. Serial computerized tomography scans and brain magnetic resonance imaging findings over a long period of time were crucial in the diagnosis of GSD. The patient required surgical repair of the CSF leak using a septal flap. Recently, the efficacy of sirolimus has been shown in several studies. Therefore, our patient was referred to a specialist in this disease, and sirolimus was started.
키워드
Gorham-Stout disease; Cerebrospinal f luid rhinorrhea; Bacterial meningitis
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