Pontine Infarction Presenting as a Syncopal Episode Associated with Primary Sjogren’s Syndrome
정다다, 최정원, 우민희, 김민지, 나상준, 오승헌, 이기욱,
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정다다 ( Chung Dar-Da )
CHA University CHA Bundang Medical Center Department of Neurology
최정원 ( Choi Jung-Won )
CHA University CHA Bundang Medical Center Department of Neurology
우민희 ( Woo Min-Hee )
CHA University CHA Bundang Medical Center Department of Neurology
김민지 ( Kim Min-Ji )
Daejeon Sun Medical Center Department of Neurology
나상준 ( Na Sang-Jun )
Konyang University College of Medicine Department of Neurology
오승헌 ( Oh Seung-Hun )
CHA University CHA Bundang Medical Center Department of Neurology
이기욱 ( Lee Kee-Ook )
CHA University CHA Bundang Medical Center Department of Neurology
Abstract
Central nervous system (CNS) involvement of primary Sjogren’s syndrome (pSS) is a controversial issue. We present a case of pontine infarction presenting as a syncopal episode associated with pSS. A 46-year-old woman was admitted to CHA Bundang Medical Center owing to right-sided weakness and dysarthria. She had no medical illness or smoking history but had a syncopal episode for the first time 3 days before. Eye and mouth dryness were found after history taking. Laboratory test results were positive for antinuclear antibodies: anti SS-A (Ro) and anti SS-B (La) antibodies. Diffusion-weighted imaging revealed high signal intensities in the left pons. Magnetic resonance angiography revealed multifocal stenoses of the basilar and bilateral vertebral arteries. Previous research on pSS mainly focused on peripheral nervous system manifestations. In our case, the associations of the CNS lesion of vasculitis with ischemia and pSS are considered pathophysiological mechanisms.
키워드
Brain stem infarctions; Syncope; Sjogren's syndrome; Central nervous system; Vasculitis
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