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¾Ç¼º¼ö¸·Á¾ÀÇ µÎ°³°­ ¿Ü ÀüÀÌ Malignant meningioma with multiple extracranial metastases: case report and review of literature

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¹ÚÅÂÀ± ( Park Tae-Yoon ) 
°¡Ãµ´ëÇб³ ÀÇ°ú´ëÇÐ ±æº´¿ø ½Å°æ¿Ü°úÇб³½Ç

À̱âÅà( Yee Gi-Taek ) 
°¡Ãµ´ëÇб³ ÀÇ°ú´ëÇÐ ±æº´¿ø ½Å°æ¿Ü°úÇб³½Ç
±èÀº¿µ ( Kim Eun-Young ) 
°¡Ãµ´ëÇб³ ÀÇ°ú´ëÇÐ ±æº´¿ø ½Å°æ¿Ü°úÇб³½Ç
±è¿ì°æ ( Kim Woo-Kyung ) 
°¡Ãµ´ëÇб³ ÀÇ°ú´ëÇÐ ±æº´¿ø ½Å°æ¿Ü°úÇб³½Ç
À¯ÂùÁ¾ ( Yoo Chan-Jong ) 
°¡Ãµ´ëÇб³ ÀÇ°ú´ëÇÐ ±æº´¿ø ½Å°æ¿Ü°úÇб³½Ç

Abstract


Meningioma is the most common benign primary intracranial tumor and rarely metastasizes. Malignant meningioma is a World Health Organization Grade III tumor and constitutes 1 to 3% of all meningioma. The prognosis of the patient of malignant meningioma is very poor because of its frequent recurrence and distant metastasis. There is no guideline concerning the management of extracranial metastasis of meningioma. A 57-old female patient presented with headache and visual disturbance due to huge skull base meningioma. She underwent subtotal mass excision with craniotomy and TSA followed by radiation therapy. However, follow-up brain magnetic resonance imaging (MRI) revealed tumor growing and the patient received additional surgical resection. After 2nd surgery the patient was presented with weakness of both lower extremities. Whole spine MRI demonstrated thoracic spine metastasis compressed spinal cord. Multiple nodules of lung and liver were noticed as well. We report a patient of malignant meningioma with multiple extracranial metastases including review of literature.

Å°¿öµå

Malignant meningioma; Extracranial metastasis; Skull base

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