혀뿌리 신경집종과 동시 발생한 중이 칼시노이드 환자 1례
A case of carcinoid tumor in the middle ear cavity with neurilemmoma in the base of tongue
이민형, 이승민, 김상연, 전범조,
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이민형 ( Lee Min-Hyeong )
가톨릭대학교 의과대학 이비인후과교실
이승민 ( Lee Soung-Min )
가톨릭대학교 의과대학 이비인후과교실
김상연 ( Kim Sang-Yeon )
가톨릭대학교 의과대학 이비인후과교실
전범조 ( Jun Beom-Cho )
가톨릭대학교 의과대학 이비인후과교실
KMID : 1037420190140020034
Abstract
Carcinoid tumors are neuroendocrine tumors which arise from the enterochromaffin cells; the neoplasms grow slowly and are usually found in the gastrointestinal and bronchopulmonary systems. Carcinoid tumors in the middle ear are uncommon since the neuroendocrine cells have not been identified in middle ear mucosa. In this case, a 46-year-old man had tinnitus in right ear for a year. From otoendoscopy findings, we observed a complete perforation of right tympanic membrane and a pinkish mass like lesion at the center of the perforated tympanic membrane. Canal wall up mastoidectomy and tympanoplasty were done, and pathological findings showed cuboidal or columnar cells with small, round, and uniform nuclei; immunohistochemistry demonstrated positive for CD 56 but negative for S-100. Ki-67 proliferation activity was low. While the patient underwent intubation for general anesthesia, a 2 cm polypoid mass was found at right base of tongue. The mass was removed by robot-assisted surgery, and the pathology demonstrated neurilemmoma. The authors report one case of carcinoid tumor that also had neurilemmoma at the same time.
키워드
Carcinoid tumor; Ear middle; Neurilemmoma
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