소아응급실에서 인플루엔자 A 바이러스 감염에 의한 열발작
Influenza A Virus Associated Febrile Seizures in Pediatric Emergency Department during Influenza Seasons
홍정석, 김미진, 정진영, 김준성, 홍은석,
소속 상세정보
홍정석 ( Hong Jung-Seok )
울산대학교병원 응급의학과
김미진 ( Kim Mi-Jin )
울산대학교병원 응급의학과
정진영 ( Jeong Jin-Young )
울산대학교병원 응급의학과
김준성 ( Kim Joon-Sung )
울산대학교병원 소아청소년과
홍은석 ( Hong Eun-Seog )
울산대학교병원 응급의학과
KMID : 1037620140010020089
Abstract
Purpose: The aims of study are to identify characteristics of febrile seizures (FS) in children confirmed with influenza A (IFA) and to compare with FS confirmed with negative influenza A (NIFA).
Methods: Between October 2013 and March 2014, 145 children visiting emergency departments because of FS were retrospectively surveyed. IFA (n=23) were compared with NIFA (n=122) regard to characteristics of FS, including age, gender, pattern of seizures, fever, history of previous FS, family history of FS, and outcomes. FS requiring lorazepam, CT (computed tomography), MRI (magnetic resonance image), CSF (cerebrospinal fluid) study were analyzed.
Results: IFA had more patients with higher body temperature over 39。C at seizure occurrence (47.8% vs. 18.0%, P=0.01), more lorazepam (52.2% vs. 25.4%, P=0.01). Seizure manifestations of IFA were significantly different with NIFA (P=0.04), in particular, but there was not the difference between simple FS and complex FS. Febrile status epilepticus was more common in IFA. FS within 12 hours febrile response (65.2% vs. 70.5%, P=0.61) and history of previous FS were common but not significantly different. There were no differences in age, gender, family history of FS and outcomes.
Conclusion: Our study suggested that IFA have higher incidence of fever and frequency in using lorazepam, and more common febrile status epilepticus than NIFA. However, there was no significant difference in the other clinical features between two groups.
키워드
Influenza A Virus; Seizures; Fevrile; Child; Emergency service; Hospital
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