신생아 약동학과 약물요법
Pharmacokinetics and drug therapy in neonates
조혜정,
소속 상세정보
조혜정 ( Cho Hye-Jung )
가천대학교 의과대학 소아과학교실
KMID : 1037620170040010005
Abstract
Neonates include both full term and preterm infants up to 28 days of age. The heterogeneity and rapid physiologic change of neonates affect all aspects of pharmacokinetics such as absorption, distribution, metabolism, and elimination. This feature should be considered in determining the dose and regimen of drug therapy in neonates. However, the research on the safety and efficacy of specific drugs is limited due to ethical and technical issues. This review article focuses on the neonatal pharmacokinetics and the rationales of drug therapy in neonates based on findings of previous studies and empirical evidence.
키워드
Bronchiolitis; Drug Administration Routes; Drug Therapy; Infants; Newborn; Pharmacokinetics
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