한국인 소아 갑상선 안병증의 발생 빈도 및 임상양상
Incidence and Clinical Characteristics of Pediatric Thyroid Associated Ophthalmopathy in Korean
이새미, 신문경, 김남영, 안희배,
소속 상세정보
이새미 ( Lee Sae-Mi )
동아대학교 의과대학 안과학교실
신문경 ( Shin Moon-Kyeong )
동아대학교 의과대학 안과학교실
김남영 ( Kim Nam-Yeong )
동아대학교 의과대학 안과학교실
안희배 ( Ahn Hee-Bae )
동아대학교 의과대학 안과학교실
KMID : 1038920190180040111
Abstract
Purpose: To investigate the incidence of pediatric thyroid associated ophthalmopathy (TAO) in Korean, compared diagnosed TAO group and non-diagnosed TAO group to evaluate clinical characteristics of pediatric TAO.
Methods: We retrospectively analyzed the medical records (ophthalmic examination, thyroid function test) 84 patients who visited ophthalmology outpatient clinic for evaluating TAO after diagnosed thyroid disease in pediatric department from July 2008 to July 2018. We compared thyroid function test diagnosed TAO group and non-diagnosed TAO group.
Results: Among 84 patients, 28 patients (33.3%) were diagnosed with TAO. None of the patients diagnosed with TAO had severe ophthalmic complication including diplopia, vision loss, visual field defect, decreasing color vision. Compared thyroid function test in two group (TAO vs. non-TAO), TSH (p = 0.07), free T4 (p = 0.07), and Tg-Ab (p = 0.3) did not show statistically significant differences in two groups. But TAO group showed high levels of TRAb and showed meaningful differences in statistically (p = 0.01).
Conclusions: The incidence rate of pediatric TAO in Korean was 33.3%. Require screening of TAO when diagnosing pediatric thyroid disease. TAO group showed high TRAb level compared with non-diagnosed TAO group. Children with high TRAb level needs attention and regular follow up.
키워드
Child; Pediatrics; Thyroid assosicated opthalmopathy
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