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Focal Xanthogranulomatous Pyelonephritis Associated with Xanthogranulomatous Cholecystitis: A Case Report

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Á¶¼þ¹® ( Cho Soong-Moon ) 
Inje University Seoul Paik Hospital Department of Radiology

±èÈ£±Õ ( Kim Ho-Kyun ) 
Inje University Seoul Paik Hospital Department of Radiology
ÀÌÇý°æ ( Lee Hye-Kyung ) 
Inje University Seoul Paik Hospital Department of Pathology
À̺´¸ð ( Lee Byung-Mo ) 
Inje University Seoul Paik Hospital Department of Surgery
±è±âȯ ( Kim Ki-Hwan ) 
Inje University Seoul Paik Hospital Department of Radiology
ÀÌ°æÀº ( Lee Kyoung-Eun ) 
Inje University Seoul Paik Hospital Department of Radiology
½ÉÀçÂù ( Shim Jae-Chan ) 
Inje University Seoul Paik Hospital Department of Radiology
Ȳ´ëÇö ( Hwang Dae-Hyun ) 
Inje University Seoul Paik Hospital Department of Radiology
À̱âÀç ( Lee Ghi-Jai ) 
Inje University Seoul Paik Hospital Department of Radiology

Abstract


Xanthogranulomatous inflammation is a rare inflammatory reaction, characterized by lipid-laden macrophages, known as xanthomas, in histopathologic examination. Aggressive xanthogranulomatous inflammation often manifests as local infiltration but does not affect distant organs unless combined with rare systemic diseases. We report a case of focal xanthogranulomatous pyelonephritis (XGP) associated with severe xanthogranulomatous cholecystitis. Focal XGP was suspected in radiologic examination that showed a cystic lesion with an infiltrative margin, which were surgically resected and confirmed in pathologic examination. To our knowledge, this is the first report of focal xanthogranulomatous pyelonephritis associated with xanthogranulomatous cholecystitis. Moreover, we found peripheral hypointensity around the cystic lesion in the T2-weighted image, probably reflecting hemorrhage and fibrosis of the xanthogranulomatous inflammation.

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Xanthogranulomatous Cholecystitis; Pyelonephritis, Xanthogranulomatous; Magnetic Resonance Imaging

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