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Serial Magnetic Resonance Imaging Findings in Hyperglycemia-Related Osmotic Demyelination Syndrome: A Case Report

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±èÁ¾Çõ ( Kim Jong-Hyuk ) 
Hanyang University College of Medicine Myongji Hospital Department of Radiology

¹Ú³ëÇõ ( Park Noh-Hyuck ) 
Hanyang University College of Medicine Myongji Hospital Department of Radiology
¹ÚÁö¿¬ ( Park Ji-Yeon ) 
Hanyang University College of Medicine Myongji Hospital Department of Radiology
±è¼±Á¤ ( Kim Seon-Jeong ) 
Hanyang University College of Medicine Myongji Hospital Department of Radiology

Abstract


We report a rare case of hyperglycemia-related osmotic demyelination syndrome (ODS) with focus on the imaging findings. A 61-year-old man with diabetes was admitted for general weakness and severe thirst. A few days later, he complained of dysarthria, dysphasia, and dysmetria. Laboratory examinations showed significant hyperglycemia, but normal electrolyte levels. Brain MRI revealed T2-signal abnormalities that were symmetrical, non-space occupying, and located in the central pons with a peripheral sparing pattern, which were suggestive of ODS. In addition, subsequent MRI revealed progression of signal hyperintensity; however, the patient's symptoms improved.

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Demyelinating Diseases; Hyperglycemia; Magnetic Resonance Imaging

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