Detection of Incidental Prostate Cancer or Urothelial Carcinoma Extension in Urinary Bladder Cancer Patients by Using Multiparametric MRI: A Retrospective Study Using Prostate Imaging Reporting and Data System Version 2.0
윤상은, 강병철, 조현혜, 박상희,
소속 상세정보
윤상은 ( Yoon Sang-Eun )
Ewha Womans University Mokdong Hospital Department of Radiology
강병철 ( Kang Byung-Chul )
Ewha Womans University Mokdong Hospital Department of Radiology
조현혜 ( Cho Hyun-Hae )
Ewha Womans University Mokdong Hospital Department of Radiology
박상희 ( Park Sang-Hui )
Ewha Womans University College of Medicine Department of Pathology
Abstract
Purpose: The study aimed to investigate the role of Prostate Imaging Reporting and Data System version 2 (PI-RADS v2) in predicting incidental prostate cancer (PCa) or urothelial carcinoma (UCa) extension in urinary bladder (UB) cancer patients.
Materials and Methods: A total of 72 UB cancer patients who underwent radical cystoprostatectomy and 3 Tesla multiparametric MRI before surgery were enrolled. PI-RADS v2 ratings were assigned by two independent radiologists. All prostate specimens were examined by a single pathologist. We compared the multiparametric MRI findings rated using PI-RADS v2 with the pathologic data.
Results: Of the 72 UB cancer patients, 29 had incidental PCa (40.3%) and 20 showed UCa extension (27.8%), with an overlap for 3 patients. With a score of 4 as the cut-off value for predicting incidental PCa, the diagnostic accuracy was 65.3%, specificity was 90.7%, and positive predictive value (PPV) was 66.7%. The diagnostic accuracy for incidental UCa extension was 47.2%, specificity was 92.3%, and PPV was 83.3%.
Conclusion: Despite the low diagnostic accuracy, the PPV and specificity were relatively high. Therefore, PI-RADS v2 scores of 1, 2, or 3 may help exclude the probability of incidental PCa or UCa extension.
키워드
Cystectomy; Magnetic Resonance Imaging; Prostate Cancer; Urinary Bladder Cancer
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