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Predictors of a Favorable Outcome after Emergent Carotid Artery Stenting in Acute Anterior Circulation Stroke Patients

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¹®°æÀÏ ( Moon Gyeong-Il ) 
Chonnam National University Medical School Department of Radiology

¹éº´Çö ( Baek Byung-Hyun ) 
Chonnam National University Medical School Department of Radiology
±è½½±â ( Kim Seul-Kee ) 
Chonnam National University Hwasun Hospital Department of Radiology
ÀÌÀ±¿µ ( Lee Yun-Young ) 
Chonnam National University Medical School Department of Radiology
ÀÌÈ¿Àç ( Lee Hyo-Jae ) 
Chonnam National University Medical School Department of Radiology
À±¿õ ( Yoon Woong ) 
Chonnam National University Medical School Department of Radiology

Abstract


Purpose: This study aimed to identify independent predictors of favorable outcomes associated with emergent carotid artery stenting (CAS) in patients with acute anterior circulation stroke.

Materials and Methods: This study included 93 patients with acute stroke who underwent emergent CAS to treat stenoocclusive lesions in the cervical internal carotid artery (ICA) within 6 hours of the onset of the associated symptoms. Data were compared between patients with and without favorable outcomes. The independent predictors of a favorable outcome were determined via logistic regression analysis (modified Rankin Scale 0?2 at 90 days).

Results: Intracranial tandem occlusion was noted in 81.7% of patients (76/93) among which (76/93), 55 of whom underwent intracranial recanalization therapy. Intracranial reperfusion was successful in 74.2% (69/93) and favorable outcomes were noted in 51.6% of patients (48/93). The mortality rate was 6.5% (6/93). In logistic regression analysis, diffusion-weighted imaging-Alberta Stroke Program Early CT Score [odds ratio (OR), 1.487; 95% confidence interval (CI), 1.018?2.173, p = 0.04], successful reperfusion (OR, 5.199; 95% CI, 1.566?17.265, p = 0.007), and parenchymal hemorrhage (OR, 0.042; 95% CI, 0.003?0.522, p = 0.014) were independently associated with a favorable outcome.

Conclusion: Baseline infarct size, reperfusion status, and parenchymal hemorrhage were independent predictors of favorable outcomes after emergent CAS to treat stenoocclusive lesions in the cervical ICA in patients with acute anterior circulation stroke.

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Carotid Artery Stenting; Acute Stroke; Thrombectomy; Prognosis

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