Prediction of Necrotizing Pancreatitis on Early CT Based on the Revised Atlanta Classification
송연선, 박희선, 유미혜, 김영준, 정성일,
소속 상세정보
송연선 ( Song Yeon-Seon )
Konkuk University School of Medicine Department of Radiology
박희선 ( Park Hee-Sun )
Konkuk University School of Medicine Department of Radiology
유미혜 ( Yu Mi-Hye )
Konkuk University School of Medicine Department of Radiology
김영준 ( Kim Young-Jun )
Konkuk University School of Medicine Department of Radiology
정성일 ( Jung Sung-Il )
Konkuk University School of Medicine Department of Radiology
Abstract
Purpose: To investigate the clinical and CT features at admission to predict the progression to necrotizing pancreatitis (NP) in patients initially diagnosed with interstitial edematous pancreatitis (IEP).
Materials and Methods: Patients with IEP who underwent contrast-enhanced CT at admission and follow-up CT (< 14 days) were included (n = 178). Two radiologists performed a consensus review of follow-up CT scans and diagnosed the type of acute pancreatitis as IEP or NP. Laboratory findings at admission were recorded. Clinical, CT, and laboratory findings were compared between the IEP-IEP group and IEP-NP group using the chi-square test and the t-test. Multivariate analysis was also performed.
Results: There were 112 and 66 patients in the IEP-IEP and the IEP-NP groups, respectively. The proportion of patients with alcohol etiology was significantly larger in the IEP-NP group. Among the CT findings, the presence of peripancreatic fluid and heterogeneous parenchymal enhancement were more frequently observed in the IEP-NP group. Among the laboratory variables, serum C-reactive protein levels and white blood cell counts were significantly higher in the IEP-NP group. Multivariate analysis revealed that the presence of peripancreatic fluid and heterogeneous parenchymal enhancement were significant findings distinguishing the two groups.
Conclusion: CT findings, such as the presence of peripancreatic fluid and heterogeneous pancreatic parenchymal enhancement, may be helpful in predicting the progression to NP in patients initially diagnosed with IEP.
키워드
Acute Pancreatitis; Acute Edematous Pancreatitis; Acute Necrotizing Pancreatitis; Pancreatic Necrosis; Peripancreatic Fat Necrosis; Computed Tomography, X-Ray
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