Molar activity of radiopharmaceuticals
최연성,
소속 상세정보
최연성 ( Choe Yearn-Seong )
Sungkyunkwan University School of Medicine Samsung Medical Center Department of Nuclear Medicine
Abstract
최근에 보고된 방사성의약품화학 분야의 명명법에 따라 그 동안 specific activity로 정의하였던 개념을 물리적인 성질을 나타내는 specific activity와 화학적 성질을 나타내는 molar activity로 세분하였다(1). 이 종설에서는 방사성의약품의 molar activity 및 중요성 등을 알아보았으며, 방사성의약품을 합성할 때 중요하게 고려하여야 한다.
Radiopharmaceuticals are used for diagnosis or therapy of diseases. According to the recent consensus nomenclature rules for radiopharmaceutical chemistry, specific activity is defined as the radioactivity per gram of radiolabeled compound and molar activity as the radioactivity per mole of radiolabeled compound. In this review, molar activity of radiopharmaceuticals is discussed in terms of its significance in nuclear imaging as well as its measurement methods.
키워드
Radiopharmaceutical; Molar activity; Specific activity; Carrier
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