한국 성인에서 흡연과 이상지질혈증의 연관성
Relationship with Smoking and Dyslipidemia in Korean Adults
신동렬, 장영근, 이재훈, 위정훈, 천동호,
소속 상세정보
신동렬 ( Shin Dong-Lyol )
효성병원 가정의학과
장영근 ( Jang Young-Keun )
효성병원 가정의학과
이재훈 ( Lee Jae-Hoon )
효성병원 가정의학과
위정훈 ( Wee Jeong-Hoon )
효성병원 가정의학과
천동호 ( Chun Dong-Ho )
녹색병원 가정의학과
Abstract
Background: Both cigarette smoking and dyslipidemia are well-established major risk factor for cardiovascular disease. The purpose of this study is to examine the relationship between cigarette smoking and dyslipidemia, using urinary cotinine level.
Methods: This was a cross-sectional study conducted in 5072 korean adults aged ≥19 years. We compared the lipid profile of smokers and non-smokers, using data from the sixth Korea National Health and Nutrition Examination Survey (2014-2015). Dyslipidemia was defined as any lipid profile abnormalities or current intake of cholesterol-lowering medication and smokers were defined as someone who are urine cotinine level ≥250 ng/ml.
Results: Male smokers revealed an increased risk for low HDL cholesterol (OR 1.46; 95% CI 1.19-1.80), high triglyceride (OR 1.41; 95% CI 1.13-1.75) and high LDL cholesterol (OR 1.71; 95% CI 1.18-2.48) compared with non-smokers, significantly. Female smokers showed increased risk for high total cholesterol (OR 1.96; 95% CI 1.19-3.23), high triglyceride (OR 2.40; 95% CI 1.48-3.90) and high LDL cholesterol (OR 3.21; 95% CI 1.75-5.90) compared with non-smokers, significantly.
Conclusion: Cigarette smoking is associated with dyslipidemia, especially in high triglyceride and LDL cholesterol in both sexes and the risk of high triglyceride and LDL cholesterol is more higher in female than male.
키워드
Smoking; Dyslipidemia; Korean adults; Urinary cotinine
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