악성 신경초종의 병리학적 검색
Malignant Schwannoma -16 eases analysis-
김정란, 장우현, 김희성,
소속 상세정보
김정란 ( )
서울대학교 의과대학 병리학교실
장우현 ( )
서울대학교 의과대학 병리학교실
김희성 ( )
서울대학교 의과대학 병리학교실
KMID : 0357919820160010052
Abstract
A histopathological study was done on 16 cartes of malignant Schwannoma that were
diagnosed at the Department of Pathology, Seoul National University during a period of
13 years, from January 1968 to December 1980. The 16 malignant Schwannomas were
distributed in the mediastinum(5), extremities(4), abdominal cavity(2) ,retroperitoneum (1)
, etc. The peripheral nerve of origin was identified in four cases, and these were
sciatic(2), femoral (1) and musculocutaneous (1).
In two cases, electron microscopy was done and the Schwann cell origin was strongly
supported by the ultrastructual findings of the tumors showing basement membranes,
interdigitated intercellular junction and desmosomes.
Histopathological features on malignant Schwannoma were characterized by
mesodermal elements that were intermingling with Schwannian elements, such as
cartilage, osteoid and rhabdomyoblasts. Two cases of malignant Schwannoma revealed
eosinophilic granular cells in the midst of the tumor tissue. These cells demonstrated
secondary lysosome in the cytoplasm electromicroscopially.
키워드
원문 및 링크아웃 정보
등재저널 정보