Àá½Ã¸¸ ±â´Ù·Á ÁÖ¼¼¿ä. ·ÎµùÁßÀÔ´Ï´Ù.

Rutheniun Red¿°»öÀ¸·Î º» ¼®¸éÁõ ÆóÆ÷º®ÀÇ ÆóÆ÷ÇǺ¹ÃþÀÇ º¯È­ The Changes of Alveolar Layer in Experimental Asbestosis Observed by ruthenium Red Stain

´ëÇѺ´¸®ÇÐȸÁö 1983³â 17±Ç 4È£ p.408 ~ 411
±èº¸¿Ï, Á¤¿ëÀÚ, ¹Ú¼¼Á¤,
¼Ò¼Ó »ó¼¼Á¤º¸
±èº¸¿Ï (  ) 
°æºÏ´ëÇб³ ÀÇ°ú´ëÇÐ º´¸®Çб³½Ç

Á¤¿ëÀÚ (  ) 
°æºÏ´ëÇб³ ÀÇ°ú´ëÇÐ º´¸®Çб³½Ç
¹Ú¼¼Á¤ (  ) 
°æºÏ´ëÇб³ ÀÇ°ú´ëÇÐ º´¸®Çб³½Ç

Abstract

¿ä ¾à
ÀúÀÚµéÀº Chrysotile asbetes¸¦ ÈíÀÔ ½ÃŲ ÈÄ ÈòÁãÀÇ ±â°ü°Ë»öÀ» Ruthenium red·Î ÇÏ¿©
º¸°í ¾òÀº ¼ºÀûÀ» ¿ä¾àÇÏ¸é ´ÙÀ½°ú °°´Ù.
1) Chrysotile asbestosÈíÀÔ ÈÄ 3ÀÏ°¿¡´Â ¥±Çü »óÇǼ¼Æ÷ÀÇ Ç¥¸é¿¡ ÁÖ·Î RR¾ç¼º¹°ÁúÀÌ °¨
¼ÒÇÏ¿´°í 5ÀÏ°¿¡ À־´Â ¥±Çü »óÇǼ¼Æ÷ÀÇ Ç¥¸éÀº ¹°·Ð, ¥°Çü »óÇǼ¼Æ÷ÀÇ Ç¥¸é¿¡¼­µµ °¨
¼ÒµÇ¾úÀ¸¸ç 7ÀÏ°³¿¡ À־´Â ÀÌ µÎ °¡Áö ¼¼Æ÷ÀÇ Ç¥¸é¿¡¼­ ´Ù°°ÀÌ °¨¼ÒµÇ¾ú´Ù. À̶§ ¥±Çü
»óÇǼ¼Æ÷Áú¿¡ ÀÖ´Â osmiophilic bodyÀÇ º¯¼ºµµ 5ÀÏ°¿¡´Â °æÇÏ¿´À¸³ª ±×ÈÄ ÀýÂ÷ º¯¼ºÀÌ ½É
ÇÏ¿´´Ù.
2) ÀÌ»óÀÇ ¼ºÀûÀ¸·Î º¸¾Æ RR¿°»ö ¾ç¼ºÀ²°ú UÇü »óÇǼ¼Æ÷ÀÇ ÅðÇ༺ º¯È­ÀÇ Á¤µµ°¡ °ÅÀÇ
ÆòÇüÇÑ °ÍÀ¸·Î º¸¾Æ ÀÌ ¹°ÁúÀÇ ´Ù°ú´Â ÀÌ ¹°ÁúÀÇ »ý»ê¼¼Æ÷ÀÇ ±â´É°ú ¹ÐÁ¢ÇÑ °ü°è¸¦ °¡Áø´Ù
°í ÇÒ ¼ö ÀÖ´Ù.
#ÃÊ·Ï#
Authors had intratracheally installated asbestos fiber to albino rats and. observed
alveolar lining layers with ruthenium red stain. The results were as follows.
1) On the third day after installation of chrysolite asbestos, ruthenium red positive
material on surface of type ¥± pneumocytes was decreased in amount. On the fifth day
that of type I pneumocytes was also decreased. On the seventh day ruthenium red
positive material was significantly decreased in both type 1 and type ¥± pneumocytes.
Degeneration of osmiophilic inclusion body appeared on the fifth day and later it more
pronounced.
2) From the above results, positivity of ruthenium red stain is parallel with degree of
type ¥± pneumocyte degradation. So the amount of ruthenium red positive material is
closely depended upon functional activity of cells producing ruthenium red positive
material.

Å°¿öµå

¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸

   

µîÀçÀú³Î Á¤º¸

KCI
KoreaMed
KAMS