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»ç¶÷ ¼Û°úüÀÇ ÇüÅÂÇÐÀû °üÂû -ÅÂ¾Æ ¹× Ãâ»ý ÈÄ ¼Û°úü 80¿¹ ºÐ¼®- A Morphological Observation on Human Pineal Glands -80 cases analysis of fetal and postnatal pineals

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Abstract

Çѱ¹ÀÎÀÇ Å¾ƿ¡¼­ ¾òÀ» ¼ö ÀÖ¾ú´ø ÅÂ·É 16ÁÖ¿¡¼­ 40ÁÖ¿¡ À̸£´Â ¼Û°úü 44¿¹¿Í »ýÈÄ 1ÀÏ
¿¡¼­ 58¼¼¿¡ À̸£´Â ¼Û°úü 36¿¹¸¦ ¿¬·É±º º°·Î ºÐ·ùÇÏ¿© ´ÙÀ½°ú °°Àº °á·ÐÀ» ¾ò¾ú´Ù.
1) ¼Û°úü´Â ÅÂ·É 16ÁÖ¿¡ ÀÌ¹Ì ±× ÇüŸ¦ °®Ãß¾î Ư¡ÀûÀÎ ¼±Á¶Á÷¾çÀ» º¸À̸ç Á¡Â÷ ÆóÆ÷
¸ð¾ç, mosaicÇüŸ¦ °ÅÃÄ »ýÈÄ 10°³¿ù¿¡´Â ¿ÏÀüÈ÷ ¼ºÀÎ ÇüŸ¦ °®Ãß°í »çÃá±â ÀÌÈÄ ¼Ò¹æÇü
¼ºÀ» ÇÑ´Ù.
2) ÅÂ·É 16ÁÖ¿¡´Â ´ëºÎºÐÀÌ ¿ø½Ã»óÀÇ ¼¼Æ÷·Î ±¸¼ºµÇ¸ç ÅÂ·É 28ÁÖ¿¡ ½Å°æ±³¼¼Æ÷·Î ºÐÈ­µÇ
°í ¼Û°úü ¼¼Æ÷¸¦ À¯µµÇÏ¸ç »ýÈÄ 10°³¿ù ÀÌÀü¿¡ ¿ÏÀüÈ÷ ¼º¼÷µÈ´Ù.
3) 80¿¹ÀÇ ¼Û°úü Áß 53¿¹¿¡¼­ melaninÀ¸·Î »ý°¢µÇ´Â °¥»ö»ö¼Ò°¡ °üÂûµÇ¾úÀ¸¸ç ƯÈ÷ ¿ø½Ã
»óÀÇ ¼¼Æ÷¿¡¼­ ´Ù¼ö ¹ß°ßµÇ¾ú°í »óÀǼ¼Æ÷°¡ °¨¼ÒÇÔ¿¡ µû¶ó ½Å°æ±³¸ð¼¼Æ÷ ¶Ç´Â ½Å°æ±³¼¼Æ÷¿¡
¼­ °üÂûµÇ¾ú´Ù. ¶Ç ÀÌ »ö¼Ò´Â »ýÈÄ 20°³¿ù ÀÌÈÄ ±Þ°ÝÈ÷ °¨¼ÒÇÏ¿´À¸¸ç 50´ë ÀÌÈÄ¿¡´Â °üÂûµÇ
Áö ¾Ê¾Ò´Ù.
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To evaluate the histological appearance of the human pineals, a morphologic study
was made based on 80 normal human Pineals. The material consisted of 44 pineals from
fetuses ranging in age from 16 to 40 gestational weeks and 36 Pineals of children and
adults ranging in age from 1 day to 58 years.
Following observation were made :
1) The pineals show a distinctive pattern of evolution in the morphology through the
entire life as judged by morphological features, such as glandular, alveolar, mosaic and
locular pattern.
2) At 16 weeks of gestation are proliferated and become ependymal cells transformed
into glial and primitive pineal parenchymal cells, that later become pinealoblasts by
before 28 weeks of gestetitan. The pineals of newborn show the pattern of adult type
by 10 months of age.
3) Melanin pigment deposits in the pineals is noted in 66 percent of the cases
examined. The pigment is first seen in glandular structure at early gestational period
and becomes risible in undifferented parenchrmal cells or glial cells. Although pigment
density varies in intensity it is generally prominent through the intrauterine period. And
after birth it becomes gradually lass prominent starting from 8 months of age and is
minimal over the age 50 fears.

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