피부 색소 진균증 1예
Chromomycosis of the Skin -A case report-
김태숙, 장우현, 송계용,
소속 상세정보
김태숙 ( )
서울대학교 의과대학 병리학교실
장우현 ( )
서울대학교 의과대학 병리학교실
송계용 ( )
중앙대학교 의과대학 병리학교실
KMID : 0357919930270050531
Abstract
색소진균(Chromomyces)은 열대 및 아열대 지방의 토양에서 흔히 발견되는 진균으로서
사람이 감염되는 경우는 주로 외상으로 손상된 피부를 통해 침투하여 국소성 결절성 피부
병변을 일으킨다. 국내에서는 1961년의 전신성 피부 병변을 일으킨 1예의 부검례와 1985년
이하부의 경결성 병변의 생검례가 각각 1예씩 보고되어 있을 뿐이나 일본에서는 이 진균증
의 발생이 증가한다는 보고가 있다.
최근 저자들은 65세된 여자의 좌측 손등에 발생한 클라도스포리움에의한 색소 진균중 1예
를 경험하였기에 광학 및 전자현미경 소견과 함께 보고하는 바이다.
#초록#
Cutaneous chromomycosis is a slow growing verrucous skin infection caused by five
species, identified as Philadophara verruscosa, Fonsecaea dermatitidis, Fonsecaea
pedrosoi, Fonsecaea compactum, Cladosporium carionii. We report a case of
chromomycosis of the skin causing by Cladosporium genus, in view of its rarity and
unique light microscopic and ultrastructural features.
This 65-year-old female had suffered from eczematous and lichenified skin lesion for
the last two years since she burned her dorsum of the left hand by boiling oil. The
lesion was slowly progressed, and ended up to the brownish hardening of the skin
covered with crusts. Skin Punch biopsy was done. Histologically, the sections revealed
typical features of chronic granulomatous inflammation along with the heavy infiltration
of the lymphocytes, plasma cells and histiocytes. Pseudocarcinomatous downgrowth of
the epidermis and microabscesses in the upper dermis were also found. Numerous thick
walled fungal organisms were noted within the giant cells and freely in the dermis,
which were positive at PAS stain, and diastase resistant. Thick mucous capsule is not
observed. The organisms showed very faint yellowish walls with a few buddings and a
few short elongated hyphae were also noted. Ultrastructurally, the fungus wall was
multilayered and inner organelles were sparse. There is no evidence of systemic
involvement, especially brain (Korea J Pathol 1993; 27:531∼534)
키워드
Skin; Cladosporium; Chromomycosis;
원문 및 링크아웃 정보
등재저널 정보