망막색소상피 선종
Adenoma of Retinal Pigment Epithelium
대한병리학회지 1996년 30권 11호 p.1053 ~ 1056
고재수, 장우현,
소속 상세정보
고재수 ( )
서울대학교 의과대학 소아과학교실
장우현 ( )
서울대학교 의과대학 병리학교실
KMID : 0357919960300111053
Abstract
안구내의 구조중에서 색소를 함유한 세포는 망막의 색소상피와 포도막의 멜라닌세포가 있
는데 이중 포도막의 멜라닌세포는 반응성 증식이 거의 없으며 종양성 증식을 주로하며 안구
내 색소종양의 대부분을 악성 흑색종이 차지한다. 망막색소상피의 종양은 반응성 과증식과
의 감별이 어려울 수도 있고, 경우에 따라서는 과증식에서 종양으로 이행한다는 보고도 있
다. 저자들은 최근 안구의 망막색소상피에 생긴 전형적인 진성 종양을 경험하였기에 간결한
문헌고찰과 함께 보고한다.
#초록#
A retinal pigment epithelium tumor is extremely rare, and the distinction from
malignant melanoma or reactive hyperplasia of pigment epithelium is mandatory,
clinically or pathologically. We report a case of adenoma of retinal pigment epithelium.
A 21 year-old female presented with a sudden decrease of visual acuity. She had no
previous inflammatory ocular disease. Fundic examination revealed an elevated mass at
the temporal side of the right eye. With the suspicion of choroidal malignant melanoma,
a right eye enucleation was done. Grossly there was a 0.7x0.5㎝ dark soft broad-based
elevated lesion in the temporal side. The anterior border was the ora serrata, and the
posterior border reached the equatorial area. The tumor was confined to the intraocular
portion. Histologically, the tumor mass was composed of the cuboidal or columnar cells
arranged in papillary, trabecular, or solid patter with fine fibrovascular stroma. The
tumor cells were heavily pigmented. The cytoplasmic border of the tumor cell was
indistinct and there was a finely granular brown pigment diffusely scattered in the
cytoplasm. Mild anisokaryosis noted, but hyperchromatism or pleomorphism were
negligible. The nucleoli were small. A transition between normal retinal pigment
epithelium and tumor mass was noted. Reactive gliosis was noted at the periphery of
the tumor.
키워드
Retina; Pigment epithelium; Adenoma; Eye;
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